MSU alumnus finds new drug target for preventing heart attack

A M.S. University’s alumni research work underpins the molecular cause of heart failures. Dr. Darshan Trivedi, a MS University alumnus and presently a researcher in Stanford University, has carried out a research which underpins the molecular cause of certain heart failures associated with hypertrophic cardiomyopathy, a disease that affects 1 in 500 individuals and is the leading cause of sudden death by heart failure for people under 35.

This work defines new paradigms for drug targeting and developing novel therapeutics associated with heart failure. Moreover, importantly, this work demonstrates the power of basic research and how it has the capability of transforming the scientific landscape related to research in cardiac biology, and development of new therapeutics.

This work co-lead authored by postdoctoral fellows Dr. Darshan Trivedi and Dr. Suman Nag from the laboratory of Dr. James Spudich in the Dept. of Biochemistry at Stanford University was recently published in Nature Structural and Molecular Biology one of the prestigious journal in medical research.

Dr. Trivedi is currently in India. He visited Faculty of Pharmacy and delivered a talk to the young researchers. The talk was organized by Dr. Prashant Murumkar, Senate member of MSU. Dr. Prashant said that he met Dr. Darshan in the year 2013 at The Pennsylvania State University, USA where he was doctoral student and since then he is in contact with him.

He joined Stanford University in 2014 and stated working at a Biochemistry Department which is ranked No 1 in the world. Almost more than 16 nobel laureates are working in the department.

This is really proud moment for the city and the university as Dr. Darshan Trivedi, born and brought up in Vadodara done Master’s from M. S. University and then did PhD in Physiology from The Pennsylvania State University, USA.

Presently he is an American Heart Association funded postdoctoral fellow at Stanford University under the expert guidance of Dr. James Spudich. This work was funded by the National Institutes of Health and the American Heart Association.